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Details
Pepstatin A (isovaleryl-pepstatin), a low molecular weight inhibitor of acid proteases, e.g. pepsin, renin, cathepsin D, and plasmepsin II. For the Plasmodium falciparum aspartyl protease plasmepsin II, Hill et al determined an IC₅₀ of 0.1 nM.
Catalog Number
N-1125
APC Number
81-5-60S
Molecular Formula
C₃₄H₆₃N₅O₉
Relative Molecular Mass
685.90
CAS Registry Number
[26305-03-3]
EINECS Number
247-600-0
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Links / Documents:
Brochures:
No brochures found.
Bachem product citations
A.Bervar et al.,
Radiology and oncology,
2,
169 (2002)
L.B.Larsen et al.,
International Dairy Journal,
10,
67 (2000)
Product citations
H.Umezawa et al.,
J. Antibiot.,
23,
263 (1970)
4031136
| Enzyme | Substrates | Inhibitors |
|---|---|---|
| Cathepsin D | ||
| Chymase | ||
| Chymosin | ||
| Retropepsin | ||
| Kexin | ||
| Pepsin A | ||
| Renin | ||
| Protein-Glutamate Methylesterase | ||
| Cathepsin E | ||
| Lysosomal Pro-X Carboxypeptidase | ||
| Peptidyl-Dipeptidase Dcp | ||
| Yapsin 1 | ||
| Gastricsin | ||
| Plasmepsin II | ||
| Napsin | ||
| Candidapepsin | ||
| HIV-2 Protease |
