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Details
Pepstatin A (isovaleryl-pepstatin), a low molecular weight inhibitor of acid proteases, e.g. pepsin, renin, cathepsin D, and plasmepsin II. For the Plasmodium falciparum aspartyl protease plasmepsin II, Hill et al determined an IC₅₀ of 0.1 nM.
Catalog Number
N-1125
APC Number
81-5-60S
Molecular Formula
C₃₄H₆₃N₅O₉
Relative Molecular Mass
685.90
CAS Registry Number
[26305-03-3]
EINECS Number
247-600-0
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Links / Documents:
Brochures:
No brochures found.
Bachem product citations
A.Bervar et al.,
Radiology and oncology,
2,
169 (2002)
Product citations
H.Umezawa et al.,
J. Antibiot.,
23,
263 (1970)
4031136
| Enzyme | Substrates | Inhibitors |
|---|---|---|
| Cathepsin D | ||
| Chymase | ||
| Chymosin | ||
| Retropepsin | ||
| Kexin | ||
| Pepsin A | ||
| Renin | ||
| Protein-Glutamate Methylesterase | ||
| Cathepsin E | ||
| Lysosomal Pro-X Carboxypeptidase | ||
| Peptidyl-Dipeptidase Dcp | ||
| Yapsin 1 | ||
| Gastricsin | ||
| Plasmepsin II | ||
| Napsin | ||
| Candidapepsin | ||
| HIV-2 Protease |
