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Availability: In stock

Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH₂ trifluoroacetate salt


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4030841.0001 1 mg Ships within 3-5 business days  
CHF 263.00
CHF 244.59 (7%)
4030841.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1,051.00
CHF 977.43 (7%)


The FRET substrate Mca-RPKPYA-Nva-WMK(Dnp)-amide was hydrolyzed 60 times more rapidly by stromelysin 1 (MMP-3) (kcat/Km= 59400 M⁻¹s⁻¹) than by interstitial collagenase (MMP-1). However, it showed little discrimination between MMP-3, gelatinase A (MMP-2) (kcat/Km= 54000 M⁻¹s⁻¹), and gelatinase B (MMP-9) (kcat/Km= 55300 M⁻¹s⁻¹). Metalloelastase (MMP-12) digested this fluorogenic substrate with a kcat/Km of 243000 M⁻¹s⁻¹.
For a fluorescent standard see M-2250.
Catalog Number M-2105
APC Number 76-4-93
Synonyms NFF-2
Molecular Formula C₇₉H₁₀₅N₁₉O₁₉S
Relative Molecular Mass 1656.89
CAS Registry Number [158584-08-8] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords MMP-3 substrate


Enzyme Substrates Inhibitors
Gelatinase A    
Gelatinase B    
Stromelysin 1    
Matrix Metalloproteinase-2 (MMP-2)    
Matrix Metalloproteinase-3 (MMP-3)    
Matrix Metalloproteinase-9 (MMP-9)    
Matrix Metalloproteinase-12 (MMP-12)