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Details
This peptide derived from the ligand binding site of the human γ-interferon (IFN-γ) receptor is an antagonist of human IFN-γ. It inhibited human IFN-γ-induced expression of HLR/DR antigen on Colo 205 cells with an approximate IC₅₀ of 35 µM. Immobilized peptide specifically bound recombinant human IFN-γ. Tyrosine substitution at residue 121 allowed facile quantification and conjugation of the peptide.
Catalog Number
H-2722
Synonyms
(Tyr¹²¹,Cys(Acm)¹²²)-IFN-γ Receptor (120-141) (human)
Molecular Formula
C₁₁₅H₁₉₄N₃₄O₃₄S
Relative Molecular Mass
2629.08
CAS Registry Number
158040-83-6
Source
Synthetic
Storage Conditions
-20 ± 5 °C
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