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4030748

Availability: In stock

Anthranilyl-HIV Protease Substrate trifluoroacetate salt
Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH₂ trifluoroacetate salt

4030748

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4030748.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 95.00
CHF 88.35 (7%)
4030748.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 378.00
CHF 351.54 (7%)
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Details

This hexapeptide FRET substrate is derived from the p24/p15 cleavage site of the viral gag-pol poly-protein. A simple, continuous fluorometric assay for HIV protease has been developed, which allows the screening of potential HIV protease inhibitors.
Values for Km (2.1 μM) and kcat (7.4 s⁻¹) were calculated from steady-state data at a low concentration of the enzyme. Excitation at 280 nm, emission at > 435 nm.
Catalog Number H-2992
Molecular Formula C₄₃H₆₅N₁₃O₁₁
Relative Molecular Mass 940.07
CAS Registry Number [133233-38-2] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords HIV protease FRET substrate
Areas of Interest Infectious Disease
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Bachem product citations

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Product citations

D.J.Porter et al., Biochemistry, 41, 1302 (2002)
M.V.Toth and G.R.Marshall, Int. J. Pept. Protein Res., 36, 544 (1990)

4030748

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