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4030746

Availability: In stock

H-Arg-Val-Leu-psi(CH₂NH)Phe-Glu-Ala-Nle-NH₂

4030746

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4030746.0001 1 mg Ships within 3-5 business days  
CHF 567.00
CHF 527.31 (7%)
4030746.0005 5 mg Ships within 3-5 business days  
CHF 2,270.00
CHF 2,111.10 (7%)
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Details

The peptide RVL-psi[CH2NH]FEA-Nle-amide containing a reduced peptide bond was found to be a competitive inhibitor of the HIV-1 protease (Ki = 50 nM).
Catalog Number N-1270
Molecular Formula C₄₀H₆₉N₁₁O₈
Relative Molecular Mass 832.06
CAS Registry Number [167875-35-6]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords HIV-1 protease inhibitor
Areas of Interest Infectious Disease
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Bachem product citations

J.M.Louis et al., Biochemistry, 54, 5414 (2015)
J.M.Louis et al., Biochemistry, 50, 4786 (2011)
Y.Tie et al., FEBS J., 272, 5265 (2005)
Y.S.Ding et al., Biochemistry, 37, 17514 (1998)
E.M.Wondrak et al., J. Biol. Chem., 271, 4477 (1996)

Product citations

M.W.Pennington et al., Peptides 1992, Proceedings of the 22nd European Peptide Symposium, Interlaken, Switzerland, p. 936, C.H.Schneider and A.N.Eberle, eds., Escom, Leiden, (1993)

4030746

Enzyme Substrates Inhibitors
Retropepsin