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Details
GLP-1 (7-36) amide is secreted from the lower small intestine and shows a strong insulinotropic effect. GLP-1 (7-36) amide is considered as the most important incretin hormone. Its action is mediated by receptors expressed by the endocrine pancreatic B-cells. Considerable interest has focused on the development of this peptide as a therapeutic strategy for non-insulin-dependent (type 2 ) diabetes mellitus and associated neuropathy.
Catalog Number
H-6795
APC Number
46-1-13
One Letter Code
HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH₂
Synonyms
Glucagon-Like Peptide 1 (7-36) amide (human, bovine, guinea pig, mouse, rat), Glucagon-Like Peptide I (7-36), amide, human, Preproglucagon (98-127) amide (human, bovine, guinea pig, mouse, rat), Proglucagon (78-107) amide (human, bovine, guinea pig, mouse, rat)
Molecular Formula
C₁₄₉H₂₂₆N₄₀O₄₅
Relative Molecular Mass
3297.68
CAS Registry Number
107444-51-9
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Insulinotropic hormone; Incretin
Application
Diabetes
Links / Documents:
Brochures:
Bachem product citations
A.E.Relling et al.,
Canadian Journal of Animal Science,
94,
357 (2014)