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Galanin (1-13)-Pro-Pro-(Ala-Leu-)₂Ala amide


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4030654.0500 0.5 mg Ships within 3-5 business days  
CHF 210.00
CHF 195.30 (7%)
4030654.1000 1 mg Ships within 3-5 business days  
CHF 368.00
CHF 342.24 (7%)


M40, a peptide containing the N-terminal galanin sequence (1-13), is an antagonist of the galanin receptor. M40 significantly antagonized galanin-induced feeding behavior at doses approximately equimolar to the active doses of rat galanin. M40 inhibited the binding of (¹²⁵I-Tyr²⁶)-galanin (porcine) in rat hypothalamic membranes with an IC₅₀ value of 15 nM. Coadministration of M40 with a muscarinic M1 agonist may enhance the efficacy of cholinergic treatments for the cognitive deficits of Alzheimer disease.
Catalog Number H-2576
APC Number 46-1-19
Synonyms M40
Molecular Formula C₉₄H₁₄₅N₂₃O₂₄
Relative Molecular Mass 1981.33
CAS Registry Number 143896-17-7
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Galanin antagonist