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Details
α-Difluoromethylornithine is a suicide inhibitor of ornithine decarboxylase. Initially developed for cancer treatment, eflornithine was found to be very efficient against trypanosomiasis. The ornithine derivative also found use in cosmetics, eflornithine-containing creams allow to reduce excessive hair growth (hirsutism).
CAS Number (net): 67037-37-0, (hydrochloride): 68278-23-9.
Catalog Number
F-2395
Synonyms
DFMO · HCl · H₂O, Eflornithine · HCl · H₂O, α-Difluoromethylornithine · HCl · H₂O
Molecular Formula
C₆H₁₂F₂N₂O₂ · HCl · H₂O
Relative Molecular Mass
236.65
CAS Registry Number
96020-91-6
EINECS Number
269-532-0
Storage Conditions
-20 ± 5 °C
Keywords
Ornithine decarboxylase inhibitor
Links / Documents:
Product citations
Merck Index, 15th ed., No. 3570,
(2013)
4030547
Enzyme | Substrates | Inhibitors |
---|---|---|
Ornithine Decarboxylase |