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4030547

Availability: In stock

H-α-Difluoro-Me-DL-Orn-OH · HCl · H₂O

4030547

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4030547.0050 50 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 73.00
CHF 67.89 (7%)
4030547.0250 250 mg Ships within 3-5 business days  
CHF 210.00
CHF 195.30 (7%)
4030547.1000 1 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 630.00
CHF 585.90 (7%)
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Details

α-Difluoromethylornithine is a suicide inhibitor of ornithine decarboxylase. Initially developed for cancer treatment, eflornithine was found to be very efficient against trypanosomiasis. The ornithine derivative also found use in cosmetics, eflornithine-containing creams allow to reduce excessive hair growth (hirsutism).
CAS Number (net): 67037-37-0, (hydrochloride): 68278-23-9.
Catalog Number F-2395
Synonyms Eflornithine · HCl · H₂O, DFMO · HCl · H₂O, α-Difluoromethylornithine · HCl · H₂O
Molecular Formula C₆H₁₂F₂N₂O₂ · HCl · H₂O
Relative Molecular Mass 236.65
CAS Registry Number [96020-91-6]
EINECS Number 269-532-0
Storage Conditions -20 ± 5 °C
Keywords Ornithine decarboxylase inhibitor
Areas of Interest Cancer Research
Cosmetic Peptides & Dermatology
Infectious Disease
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Product citations

Merck Index, 15th ed., No. 3570, (2013)
C.Burri and R.Brun, Parasitol. Res., 90 Supp. 1, S49 (2003)
S.M.Fischer et al., Carcinogenesis, 22, 83 (2001)
C.Carrillo et al., Biochem. Biophys. Res. Commun., 279, 663 (2000)
F.L.Meyskens and E.W.Gerner, Clin. Cancer Res., 5, 945 (1999)
A.Lipton et al., Cancer, 63, 433 (1989)

4030547

Enzyme Substrates Inhibitors
Ornithine Decarboxylase