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Details
The FRET peptide Dnp-RPLALWRS is the best fluorogenic substrate developed for matrilysin (also called punctuated metalloproteinase 1, PUMP-1 or MMP-7) thus far. In addition to good kinetic parameters (kcat/Km = 1.9 · 10⁵ M⁻¹s⁻¹), it showed good solubility in assay buffer.
Catalog Number
M-2205
APC Number
76-4-91
One Letter Code
Dnp-RPLALWRS
Synonyms
MMP-7 Substrate (Matrilysin Substrate, PUMP-1 Substrate), Fluorogenic
Molecular Formula
C₅₂H₇₇N₁₇O₁₄
Relative Molecular Mass
1164.29
CAS Registry Number
172666-82-9
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Cancer Research
Inflammation Research
Inflammation Research
Links / Documents:
Bachem product citations
Product citations
4030541
| Enzyme | Substrates | Inhibitors |
|---|---|---|
| Matrilysin | ||
| Matrix Metalloproteinase-7 (MMP-7) |
