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4030484

Availability: In stock

Ac-Ile-Glu-Pro-Asp-AMC

4030484

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4030484.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 210.00
CHF 195.30 (7%)
4030484.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 840.00
CHF 781.20 (7%)

Details

Ac-IEPD-AMC is a preferred substrate sequence of granzyme B, a mammalian serine protease involved in the induction of rapid target cell death by cytotoxic lymphocytes.
Catalog Number I-1835
APC Number 81-8-02
One Letter Code Ac-IEPD-AMC
Synonyms Ac-IEPD-AMC
Molecular Formula C₃₂H₄₁N₅O₁₁
Relative Molecular Mass 671.71
CAS Registry Number [216757-33-4]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Caspase-8 substrate; Granzyme B substrate
Areas of Interest Apoptosis & Necrosis
Links / Documents:
Brochures:

Bachem product citations

K.Barczyk et al., Blood, 116, 446 (2010)
J.H.Velthuis et al., Biochem. Pharmacol., 69, 463 (2005)
S.Mahrus et al., J. Biol. Chem., 279, 54275 (2004)
S.Mahrus et al., J. Biol. Chem., 279, 54275 (2004)
J.Frank et al., Int. J. Cancer, 107, 941 (2003)

Product citations

J.L.Harris et al., J. Biol. Chem., 273, 27364 (1998)

4030484

Enzyme Substrates Inhibitors
Caspase-8 (MACH; FLICE; Mch5)    
Granzyme B    
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