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Availability: In stock

Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH trifluoroacetate salt


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4030476.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 263.00
CHF 244.59 (7%)


Specific highly fluorescent FRET substrate for the determination of caspase-1 (ICE) and caspase-1-like enzyme activities. Cleavage of Mca-YVADAPK(Dnp) at the P1 Asp residue results in a continuous fluorescent assay monitored at an emission wavelength of 392 nm. Caspase-3 (apopain, CPP-32) is only weakly active on this substrate. Both caspase-1 and caspase-3 are involved in apoptosis. A specific substrate for renal ACE 2.
Catalog Number M-2195
APC Number 81-7-96
One Letter Code Mca- YVADAPK(Dnp)
Synonyms Mca-YVADAPK(Dnp)
Molecular Formula C₅₃H₆₄N₁₀O₁₉
Relative Molecular Mass 1145.15
CAS Registry Number 189696-01-3
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords ICE FRET substrate
Application Apoptosis & Necrosis


Enzyme Substrates Inhibitors
Caspase-1 (ICE)    
Angiotensin-converting Enzyme 2