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Details
Specific highly fluorescent FRET substrate for the determination of caspase-1 (ICE) and caspase-1-like enzyme activities. Cleavage of Mca-YVADAPK(Dnp) at the P1 Asp residue results in a continuous fluorescent assay monitored at an emission wavelength of 392 nm. Caspase-3 (apopain, CPP-32) is only weakly active on this substrate. Both caspase-1 and caspase-3 are involved in apoptosis.
A specific substrate for renal ACE 2.
Catalog Number
M-2195
APC Number
81-7-96
One Letter Code
Mca- YVADAPK(Dnp)
Synonyms
Mca-YVADAPK(Dnp)
Molecular Formula
C₅₃H₆₄N₁₀O₁₉
Relative Molecular Mass
1145.15
CAS Registry Number
189696-01-3
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
ICE FRET substrate
Application
Apoptosis & Necrosis
Links / Documents:
Bachem product citations
4030476
| Enzyme | Substrates | Inhibitors |
|---|---|---|
| Caspase-1 (ICE) | ||
| Angiotensin-converting Enzyme 2 |
