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Details
The acylation of the N-terminus of (D-Arg⁰,Hyp³,Thi⁵·⁸,D-Phe⁷)-bradykinin with 1-adamantaneacetic acid results in an antagonist with ten times more potency. This new analogue suggests new possibilities for the design of more potent and selective bradykinin antagonists.
Catalog Number
H-1114
APC Number
18-1-70
Synonyms
[N-Admantaneacetyl-DArg0-Hyp3, Thi5,8, DPhe7] Bradykinin
Molecular Formula
C₆₈H₉₉N₁₉O₁₄S₂
Relative Molecular Mass
1470.79
CAS Registry Number
[130942-96-0]
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Bradykinin antagonist
Areas of Interest
Cardiovascular System & Diseases
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