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Details
C-ANF 4-23 binds with high affinity to approximately 99% of ANF receptors in the isolated perfused rat kidney. It competes effectively with biologically active atrial peptides for binding sites but is devoid of agonist or antagonist action on the generation of cGMP in vascular smooth muscle and endothelial cells in culture.
Catalog Number
H-3134
APC Number
14-1-45
One Letter Code
RSSCFGGRIDRIGAC-NH₂
Synonyms
(Des-Gln¹⁸,des-Ser¹⁹,des-Gly²⁰·²²,des-Leu²¹)-Atrial Natriuretic Peptide (4-23) amide (mouse, rabbit, rat), C-ANF (4-23), Des[Gln18, Ser19, Gly20,22, Leu21] ANP (4-23), amide, rat
Molecular Formula
C₆₄H₁₀₇N₂₅O₁₉S₂
Relative Molecular Mass
1594.84
CAS Registry Number
111863-73-1
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
ANF receptor-binding peptide
Application
Cardiovascular System & Diseases
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