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4030330

Availability: In stock

Amyloid β-Protein (1-16) trifluoroacetate salt
H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-OH trifluoroacetate salt

4030330

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4030330.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 71.00
CHF 66.03 (7%)
4030330.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 102.00
CHF 94.86 (7%)

Details

The Cu²⁺ complex of this soluble amyloid β-protein fragment showed significant oxidative activities toward the catechol-like substrate 1,2,3-trihydroxylbenzene (pyrogallol) and plasmid DNA cleavage. The N-terminal Aβ fragments Aβ1-14, Aβ1-15, and Aβ1-16 are elevated in cell media and in CSF in response to γ-secretase inhibitor treatment. The fragments can serve as biomarkers in clinical studies of the effect of such inhibitors.
Catalog Number H-2958
APC Number 62-0-36
One Letter Code DAEFRHDSGYEVHHQK
Synonyms β-Amyloid (1-16), human
Molecular Formula C₈₄H₁₁₉N₂₇O₂₈
Relative Molecular Mass 1955.03
CAS Registry Number 131580-10-4
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Biomarker
Application Alzheimer's Disease
Links / Documents:
Brochures:

Bachem product citations

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Product citations

E.Portelius et al., Neurodegener. Dis., 10, 138 (2012)
E.Portelius et al., Curr. Pharm. Des., 17, 2594 (2011)
E.Portelius et al., Alzheimer Res. Ther., 2, 7 (2010)
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G.F.da Silva et al., J. Biol. Chem., 280, 16601 (2005)
K.Zou et al., J. Neurosci., 22, 4833 (2002)