Shopping Cart - CHF 0.00

You have no items in your shopping cart.

  • Home  » 
  • 4030330
Return to Previous Page
4030330

Availability: In stock

Amyloid β-Protein (1-16) trifluoroacetate salt
H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-OH trifluoroacetate salt

4030330

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4030330.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 71.00
CHF 66.03 (7%)
4030330.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 102.00
CHF 94.86 (7%)

Details

The Cu²⁺ complex of this soluble amyloid β-protein fragment showed significant oxidative activities toward the catechol-like substrate 1,2,3-trihydroxylbenzene (pyrogallol) and plasmid DNA cleavage. The N-terminal Aβ fragments Aβ1-14 (H-7372), Aβ1-15 (H-6368), and Aβ1-16 are elevated in cell media and in CSF in response to γ-secretase inhibitor treatment. The fragments can serve as biomarkers in clinical studies of the effect of such inhibitors.
Catalog Number H-2958
APC Number 62-0-36
One Letter Code DAEFRHDSGYEVHHQK
Synonyms β-Amyloid (1-16), human
Molecular Formula C₈₄H₁₁₉N₂₇O₂₈
Relative Molecular Mass 1955.03
CAS Registry Number 131580-10-4
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Biomarker
Areas of Interest Alzheimer's Disease
Links / Documents:
Brochures:

Bachem product citations

M.Manea et al., Int. J. Peptide Res. Ther., 21, 125 (2015)
M.Hanenberg et al., J. Biol. Chem., 289, 27080 (2014)
Y.Lu et al., J. Am. Soc. Mass Spectrom., 24, 454 (2013)
W.A.Gunderson et al., J. Am. Chem. Soc., 134, 18330 (2012)
E.Portelius et al., Mol. Neurodegener., 5, 2 (2010)
M.Kamali-Moghaddam et al., BMC Neurosci., 11, 124 (2010)
W.Ni et al., Anal. Chem., 82, 7485 (2010)
Y.Lu et al., Metallomics, 2, 474 (2010)
J.Shearer and V.A.Szalai, J. Am. Chem. Soc., 130, 17826 (2008)
J.W.Karr and V.A.Szalai, Biochemistry, 47, 5006 (2008)
R.Liu et al., J. Neurosci. Res., 75, 162 (2004)
R.Liu et al., Biochemistry, 43, 6959 (2004)
R.Liu et al., Biochemistry, 43, 9999 (2004)
A.M.Szczepanik et al., J. Neurochem., 77, 304 (2001)

Product citations

E.Portelius et al., Neurodegener. Dis., 10, 138 (2012)
E.Portelius et al., Curr. Pharm. Des., 17, 2594 (2011)
E.Portelius et al., Alzheimer Res. Ther., 2, 7 (2010)
M.K.Mustafa et al., Biosens. Bioelectron., 26, 1332 (2010)
G.F.da Silva et al., J. Biol. Chem., 280, 16601 (2005)
K.Zou et al., J. Neurosci., 22, 4833 (2002)