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The Cu²⁺ complex of this soluble amyloid β-protein fragment showed significant oxidative activities toward the catechol-like substrate 1,2,3-trihydroxylbenzene (pyrogallol) and plasmid DNA cleavage.
The N-terminal Aβ fragments Aβ1-14 (H-7372), Aβ1-15 (H-6368), and Aβ1-16 are elevated in cell media and in CSF in response to γ-secretase inhibitor treatment. The fragments can serve as biomarkers in clinical studies of the effect of such inhibitors.
The N-terminal Aβ fragments Aβ1-14 (H-7372), Aβ1-15 (H-6368), and Aβ1-16 are elevated in cell media and in CSF in response to γ-secretase inhibitor treatment. The fragments can serve as biomarkers in clinical studies of the effect of such inhibitors.
Catalog Number
H-2958
APC Number
62-0-36
One Letter Code
DAEFRHDSGYEVHHQK
Synonyms
β-Amyloid (1-16), human
Molecular Formula
C₈₄H₁₁₉N₂₇O₂₈
Relative Molecular Mass
1955.03
CAS Registry Number
[131580-10-4] net
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Biomarker
Areas of Interest
Alzheimer's Disease
Links / Documents:
Bachem product citations
M.Manea et al.,
Int. J. Peptide Res. Ther.,
21,
125 (2015)
