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Details
(Pyr³)-Amyloid β-Protein (3-42) was found to be the predominant amyloid β-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. Therefore, (Pyr³)-Aβ (3-42) is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits. Nussbaum et al. studies the Prion-like behaviour and tau-dependent cytotoxicity of the truncated Aβ sequence.
Catalog Number
H-4796
APC Number
62-0-21
One Letter Code
pEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Synonyms
(Glp3) β-Amyloid (3-42)
Molecular Formula
C₁₉₆H₂₉₉N₅₃O₅₅S
Relative Molecular Mass
4309.92
CAS Registry Number
183449-57-2
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Alzheimer's Disease
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