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Details
The VLA-4 inhibitor BIO-1211 based on the LDVP motif represents a selective, tight-binding inhibitor of integrin α₄β₁ achieved by appending an optimal organic group to the N-terminus of the peptide (Kd = 70 pM). Moreover, this inhibitor exhibited > 200-fold selectivity for the activated form of the integrin α₄β₁ receptor.
Catalog Number
N-1765
Molecular Formula
C₃₆H₄₈N₆O₉
Relative Molecular Mass
708.81
CAS Registry Number
187735-94-0
Source
Synthetic
Storage Conditions
-20 ± 5 °C
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