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Details
Cell-permeable and reversible inhibitor of cathepsin L, a lysosomal cysteine protease ( IC₅₀ 1.9 nM).
1-Naphthalenylsulfonyl-IW-CHO inhibited the release of Ca²⁺ and hydroxyproline from bone in an in vitro bone culture system. It should be useful for the treatment of osteoporosis.
Catalog Number
N-1760
Molecular Formula
C₂₇H₂₉N₃O₄S
Relative Molecular Mass
491.61
CAS Registry Number
161709-56-4
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Cathepsin L inhibitor
Application
Osteoporosis Research
Links / Documents:
Bachem product citations
Product citations
4029154
| Enzyme | Substrates | Inhibitors |
|---|---|---|
| Cathepsin L |
