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4029154

Availability: In stock

1-Naphthalenylsulfonyl-Ile-Trp-aldehyde

4029154

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4029154.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 357.00
CHF 332.01 (7%)
4029154.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1,429.00
CHF 1,328.97 (7%)

Details

Cell-permeable and reversible inhibitor of cathepsin L, a lysosomal cysteine protease ( IC₅₀ 1.9 nM). 1-Naphthalenylsulfonyl-IW-CHO inhibited the release of Ca²⁺ and hydroxyproline from bone in an in vitro bone culture system. It should be useful for the treatment of osteoporosis.
Catalog Number N-1760
Molecular Formula C₂₇H₂₉N₃O₄S
Relative Molecular Mass 491.61
CAS Registry Number 161709-56-4
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Cathepsin L inhibitor
Application Osteoporosis Research
Links / Documents:

Bachem product citations

N.J.Nkemgu et al., Int. J. Antimicrob. Agents, 22, 155 (2003)

Product citations

T.Yasuma et al., J. Med. Chem., 41, 4301 (1998)

4029154

Enzyme Substrates Inhibitors
Cathepsin L