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Details
Apelin-13, generated from apelin-36, is an endogenous peptide ligand for the human APJ receptor, a putative receptor protein related to the angiotensin receptor (AT1). Apelin-13 exerted an acidification-rate-promoting activity in the CHO cells expressing the APJ receptor with a median effective concentration (EC₅₀) value of 0.37 nM. In a study of Valle et al. chronic central administration of apelin-13 over 10 days increased food intake, body weight, locomotor activity and body temperature in C57BL/6 mice.
Catalog Number
H-4566
APC Number
12-1-15
One Letter Code
QRPRLSHKGPMPF
Molecular Formula
C₆₉H₁₁₁N₂₃O₁₆S
Relative Molecular Mass
1550.85
CAS Registry Number
217082-58-1
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Mediator of vasodilation
Application
Obesity Research
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