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Details
The chimeric peptide galparan powerfully stimulated insulin secretion from isolated rat pancreatic islets in a reversible and dose-dependent manner. Galparan also promoted exocytosis in depolarized B cells from normal rats as well as insulin-resistant type II diabetic Goto-Kakizaki (GK) rats. Galparan acts at a yet unknown site, different from that used by mastoparan.
Catalog Number
H-4188
One Letter Code
GWTLNSAGYLLGPINLKALAALAKKIL-NH₂
Synonyms
Galparan
Molecular Formula
C₁₃₃H₂₂₂N₃₄O₃₂
Relative Molecular Mass
2809.44
CAS Registry Number
[177352-81-7]
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Areas of Interest
Diabetes
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