6-(7-Nitro-benzo[2,1,3]oxadiazol-4-ylamino)-hexanoyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys((7-dimethylaminocoumarin-4-yl)-acetyl)-NH₂ 4028275

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6-(7-Nitro-benzo[2,1,3]oxadiazol-4-ylamino)-hexanoyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys((7-dimethylaminocoumarin-4-yl)-acetyl)-NH₂ trifluoroacetate salt

4028275

Product No.	Pack Size	Available	ADS InfoAnalytical Data Sheet	Unit Price	Online Order Price	Qty
4028275.0001	1 mg	Ships within 1 business day	ADSExemplary Data Sheet of a current available lot.	CHF 462.00	CHF 429.66 (7%)
4028275.0005	5 mg	Ships within 1 business day	ADSExemplary Data Sheet of a current available lot.	CHF 1,849.00	CHF 1,719.57 (7%)

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Details

NBD-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys(DMC)-NH₂ (NBD-RPKPLA-Nva-WK(DMC) amide) is an excellent fluorogenic substrate for hydrolysis of the matrix metalloproteinase stromelysin (MMP-3). This FRET substrate exhibits high sensitivity and improves accuracy at lower substrate turnover. It has a kcat/Km value of 2.14 x 10⁴ M⁻¹s⁻¹ and can be easily detected at 350 nm (excitation) and 465 nm (emission). Therefore this compound is a suitable tool for high-throughput inhibitor screening.

Catalog Number M-2300

Synonyms NBD-ε-aminocaproyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys(DMACA)-NH₂

Molecular Formula C₇₈H₁₁₁N₂₁O₁₆

Relative Molecular Mass 1598.87

CAS Registry Number [945414-97-1]

Source Synthetic

Storage Conditions -20 ± 5 °C

Areas of Interest Cancer Research
Inflammation Research

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