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Details
Buserelin is a longer acting synthetic peptide analog of the naturally occurring gonadotropin-releasing hormone (GnRH/LHRH). Substitution of glycine in position 6 by D-serine and that of glycinamide in position 10 by ethylamide, leads to a nonapeptide with a significantly enhanced LHRH effect. The effects of buserelin on follicle-stimulating hormone (FSH) and luteinizing hormone (LH) release are approximately 20 to 170 times higher than those of natural LHRH.
CAS Number (buserelin acetate): 68630-75-1.
Catalog Number
H-4224
APC Number
54-1-23
Synonyms
[DSer(tBu)6, Des-Gly10] LH-RH, Ethyl Amide, Buserelin
Molecular Formula
C₆₀H₈₆N₁₆O₁₃
Relative Molecular Mass
1239.44
CAS Registry Number
57982-77-1
EINECS Number
261-061-9
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
GnRH agonist
Application
Cancer Research
Veterinary Medicine
Veterinary Medicine
Links / Documents:
Brochures:
Product citations
Merck Index, 15th ed., No. 1506,
(2013)