×

Cookie Settings

We use cookies so that we can offer you the best possible website experience. This includes cookies which are necessary for the operations of the website, as well as cookies that are only used for anonymous statistical purposes, for comfort settings or to display personalized content. Please note that based on your settings, it is possible that not all functionalities of the website will be available. You can find further information in our privacy policy.

Please make your personal preference here:

Imprint

 
 
Shopping Cart - CHF 0.00

You have no items in your shopping cart.

  • Home  » 
  • 4027934
Return to Previous Page
4027934

Availability: In stock

N-ω-Hydroxy-L-norarginine acetate salt

4027934

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4027934.0050 50 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 105.00
CHF 97.65 (7%)
4027934.0250 250 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 442.00
CHF 411.06 (7%)
4027934.1000 1 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1,324.00
CHF 1,231.32 (7%)

Details

N-ω-Hydroxy-L-norarginine (or N-ω-Hydroxy-nor-L-arginine) is a most potent reversible inhibitor of arginase. At pH 7.4 nor-NOHA inhibited the rat liver arginase-dependent hydrolysis of H-Arg-OH with an EC₅₀ = 2 ± 0.5 µM and the arginase activity of mouse macrophages with an EC₅₀ value of 50 ± 10 µM.
Catalog Number F-3685
Synonyms L-2-Amino-4-(2'-hydroxyguanidino)-butyric acid, nor-NOHA, H-Nar(OH)-OH
Molecular Formula C₅H₁₂N₄O₃
Relative Molecular Mass 176.18
CAS Registry Number 189302-40-7
Storage Conditions -20 ± 5 °C
Keywords Arginase inhibitor
Links / Documents:

Bachem product citations

O.Kovamees et al., J. Intern. Med., 279, 477 (2016)
H.Hu et al., Biochem. Biophys. Res. Commun., 464, 840 (2015)
T.Toya et al., Physiol. Rep., 2, (2014)
C.S.Hackett et al., Cell Rep., 9, 1034 (2014)
J.Yang et al., Proc. Natl. Acad. Sci. USA, 110, 15049 (2013)
Y.Akazawa et al., Free Radic. Res., 47, 137 (2013)
Z.Havlinova et al., Xenobiotica, 43, 886 (2013)
A.Shemyakin et al., Circulation, 126, 2943 (2012)
A.T.Gonon et al., PLoS One, 7, e42038 (2012)
C.Prati et al., Arthritis Res. Ther., 14, R130 (2012)
Y.C.Martins et al., PLoS One, 7, e32048 (2012)
Y.C.Martins et al., PLoS One, 7, e32048 (2012)
H.Fu et al., Eur. J. Immunol., 41, 2997 (2011)
J.Gronros et al., Am. J. Physiol. Heart Circ. Physiol., 300, H1174 (2011)
T.Bagnost et al., J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 856, 113 (2011)
C.Andre et al., J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 878, 2826 (2010)
C.Jung et al., Cardiovasc. Res., 85, 147 (2010)
C.Luckner-Minden et al., J. Leukoc. Biol., 87, 1125 (2010)
J.M.Bratt et al., Toxicol. Appl. Pharmacol., 242, 1 (2010)
T.Bagnost et al., Cardiovasc. Res., 87, 569 (2010)
J.Oberlies et al., J. Immunol., 182, 5259 (2009)
M.Modolell et al., PLoS Negl. Trop. Dis., 3, e480 (2009)
M.Rogers et al., PLoS Pathog., 5, e1000555 (2009)
G.Jeyabalan et al., Nitric Oxide, 19, 29 (2008)
K.M.Reid et al., Am. J. Physiol. Gastrointest. Liver Physiol., 292, G512 (2007)
A.G.Estevez et al., J. Neurosci., 26, 8512 (2006)
A.Yeramian et al., J. Immunol., 176, 5918 (2006)
A.Yeramian et al., J. Immunol., 176, 5918 (2006)
M.Munder et al., Blood, 108, 1627 (2006)
L.Brys et al., J. Immunol., 174, 6095 (2005)
P.Kropf et al., FASEB J., 19, 1000 (2005)
Y.Liu et al., J. Immunol., 170, 5064 (2003)
D.M.Colleluori and D.E.Ash, Biochemistry, 40, 9356 (2001)

Product citations

D.M.Colleluori and D.E.Ash, Biochemistry, 40, 9356 (2001)
J.Custot et al., J. Am. Chem. Soc., 119, 4086 (1997)

4027934

Enzyme Substrates Inhibitors
Arginase