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Promobanner OCT 2020

4027888

Availability: In stock

MG 132
Z-Leu-Leu-Leu-aldehyde

4027888

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4027888.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 210.00
CHF 195.30 (7%)

Details

Z-LLL-CHO (MG132) was shown to initiate neurite outgrowth in PC12 cells with an optimal concentration of 20 nM and to be a very strong inhibitor of 20S proteasome and of calpain.
Catalog Number N-1635
APC Number 81-5-15
Synonyms MG 132
Molecular Formula C₂₆H₄₁N₃O₅
Relative Molecular Mass 475.63
CAS Registry Number 133407-82-6
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Calpiain and proteasome inhibitor
Application Cancer Research
Links / Documents:

Bachem product citations

D.H.Han et al., Nat. Commun., 5, 5633 (2014)
H.Sorimachi et al., Biol. Chem., 393, 853 (2012)
F.Cerruti et al., J. Comp. Pathol., 143, 164 (2010)
R.J.Ingham et al., J. Biol. Chem., 280, 34133 (2005)
C.Huber et al., Digestion, 65, 87 (2002)
N.J.Nkemngu et al., Antimicrob. Agents Chemother., 46, 2038 (2002)

Product citations

S.Tsubuki et al., J. Biochem., 119, 572 (1996)
T.J.Jensen et al., Cell, 83, 129 (1995)
Y.Saito et al., Neurosci. Lett., 120, 1 (1990)

4027888

Enzyme Substrates Inhibitors
Calpain    
Multicatalytic Endopeptidase Complex    
Proteasome Endopeptidase Complex