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4027875

Availability: In stock

Ac-Glu-Ser-Met-Asp-aldehyde (pseudo acid)

4027875

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4027875.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 210.00
CHF 195.30 (7%)

Details

The peptide aldehyde Ac-ESMD-CHO corresponds to one of the cleavage sites of the inactive 32 kD caspase-3 precursor (amino acids 25-28). In a concentration range of 2.5 - 5 µM, it blocked the formation of the p17 subunit and concomitantly induced the accumulation of the p20 peptide.
Catalog Number N-1625
APC Number 81-7-82
One Letter Code Ac-ESMD-CHO
Synonyms Ac-Glu-Ser-Met-Asp-CHO, Ac-ESMD-CHO
Molecular Formula C₁₉H₃₀N₄O₁₀S
Relative Molecular Mass 506.53
CAS Registry Number 191338-87-1
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Procaspase-3 inhibitor
Application Apoptosis & Necrosis
Links / Documents:

Product citations

Z.Han et al., J. Biol. Chem., 272, 13432 (1997)

4027875

Enzyme Substrates Inhibitors
"Caspase 3 Precursor Protease (Pro-CPP-32; Pro-Yama; Pro-Apopain)    
Granzyme B"