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Details
The peptide aldehyde Ac-ESMD-CHO corresponds to one of the cleavage sites of the inactive 32 kD caspase-3 precursor (amino acids 25-28). In a concentration range of 2.5 - 5 µM, it blocked the formation of the p17 subunit and concomitantly induced the accumulation of the p20 peptide.
Catalog Number
N-1625
APC Number
81-7-82
One Letter Code
Ac-ESMD-CHO
Synonyms
Ac-Glu-Ser-Met-Asp-CHO, Ac-ESMD-CHO
Molecular Formula
C₁₉H₃₀N₄O₁₀S
Relative Molecular Mass
506.53
CAS Registry Number
191338-87-1
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Procaspase-3 inhibitor
Application
Apoptosis & Necrosis
Links / Documents:
Product citations
4027875
| Enzyme | Substrates | Inhibitors |
|---|---|---|
| "Caspase 3 Precursor Protease (Pro-CPP-32; Pro-Yama; Pro-Apopain) | ||
| Granzyme B" |
