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Details
Endomorphin-1 (YPWF-amide) is the most potent and selective endogenous agonist for the mu-opiate receptor so far described (Ki = 360 pM; 4'000- and 15'000-fold preference over the delta and kappa receptors). It may be a natural ligand for this receptor.
Endomorphin-1 has been shown to inhibit the aggregation of Aβ in vitro and is effective in vivo.
Catalog Number
H-4002
APC Number
23-1-10
One Letter Code
YPWF-NH₂
Molecular Formula
C₃₄H₃₈N₆O₅
Relative Molecular Mass
610.71
CAS Registry Number
189388-22-5
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Opiate receptor agonist
Application
Alzheimer's Disease
Opioid Research
Opioid Research
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