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Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4027662.0005 5 mg Ships within 3-5 business days  
CHF 210.00
CHF 195.30 (7%)
4027662.0025 25 mg Ships within 3-5 business days  
CHF 840.00
CHF 781.20 (7%)


With a kcat/Km of 3.3 · 10⁶ M⁻¹s⁻¹ the fluorogenic caspase-1 substrate Ac-WEHD-AMC is cleaved 50-fold more efficiently than I-1630. This result indicates that the optimal tetrapeptide recognition sequence for caspase-1 is Trp-Glu-His-Asp and not Tyr-Val-Ala-Asp.
Catalog Number I-1715
APC Number 81-7-18
One Letter Code Ac-WEHD-AMC
Synonyms Ac-WEHD-AMC
Molecular Formula C₃₈H₄₀N₈O₁₁
Relative Molecular Mass 784.78
CAS Registry Number 189275-74-9
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords ICE substrate
Areas of Interest Apoptosis & Necrosis


Enzyme Substrates Inhibitors
Caspase-1 (ICE)