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4027601

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Acetyl-(Nle⁴,Asp⁵,D-2-Nal⁷,Lys¹⁰)-cyclo-α-MSH (4-10) amide trifluoroacetate salt
Ac-Nle-cyclo(-Asp-His-D-2-Nal-Arg-Trp-Lys-NH₂) trifluoroacetate salt

4027601

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4027601.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 105.00
CHF 97.65 (7%)
4027601.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 420.00
CHF 390.60 (7%)
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Details

Screening analogs of the cyclic lactam melanocortin agonist MTII led to the identification of the agoutimimetic SHU9119. The cyclopeptide SHU9119 shares pharmacological properties with the agouti peptide in that it is a potent antagonist of the melanocortin-4 receptor and a less potent antagonist of the melanocortin-3 receptor.
Catalog Number H-3952
Synonyms SHU9119
Molecular Formula C₅₄H₇₁N₁₅O₉
Relative Molecular Mass 1074.25
CAS Registry Number [168482-23-3] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Obesity Research
Pituitary & Hypothalamic Hormones
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Bachem product citations

S.Cerritelli et al., PLoS One, 11, e0153187 (2016)
S.R.Tala et al., Bioorg. Med. Chem. Lett., 25, 5708 (2015)
M.K.Kaneva et al., Biochem. Pharmacol., 92, 336 (2014)
S.Veiksina et al., Biochim. Biophys. Acta, 1838, 372 (2014)
K.L.Chapman and J.B.Findlay, Biochim. Biophys. Acta, 1828, 535 (2013)
P.Li et al., Exp. Physiol., 98, 435 (2013)
C.Blouet and G.J.Schwartz, Cell Metab., 16, 579 (2012)
E.Ishida et al., PLoS One, 7, e50918 (2012)
B.G.Irani et al., Eur. J. Pharmacol., 660, 80 (2011)
G.Yang et al., Anim. Reprod. Sci., 122, 367 (2010)
J.E.Blevins et al., Am. J. Physiol. Regul. Integr. Comp. Physiol., 296, R476 (2009)
C.Blouet et al., J. Neurosci., 29, 8302 (2009)
E.U.Do et al., Biochem. Biophys. Res. Commun., 343, 1094 (2006)
J.J.Hillebrand et al., Eur. Neuropsychopharmacol., 16, 403 (2006)
A.Cox et al., FEBS Lett., 579, 285 (2005)
K.E.Wortley et al., Cell Metab., 2, 421 (2005)
C.R.Barb et al., J. Endocrinol., 181, 39 (2004)
M.Doghman et al., Endocrinology, 145, 541 (2004)
W.A.Nijenhuis et al., Eur. J. Pharmacol., 495, 145 (2004)
W.A.Nijenhuis et al., Eur. J. Pharmacol., 495, 145 (2004)
A.N.van den Pol et al., Neuron, 42, 635 (2004)
S.J.Getting et al., J. Pharmacol. Exp. Ther., 306, 631 (2003)
S.Obici et al., Nat. Med., 8, 1376 (2002)
C.Polidori and N.Geary, Peptides, 23, 1697 (2002)

Product citations

W.Fan et al., Nature, 385, 165 (1997)
V.J.Hruby et al., J. Med. Chem., 38, 3454 (1995)