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4027536

Availability: In stock

Z-Val-Ala-Asp-AMC

4027536

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4027536.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 189.00
CHF 175.77 (7%)
4027536.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 757.00
CHF 704.01 (7%)
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Details

The fluorogenic substrate Z-VAD-AMC is cleaved by caspase-1 to generate free AMC. The cleavage was monitored by using an excitation wavelength of 365 nm and determining the emission at 450 nm.
Catalog Number I-1710
APC Number 81-7-85
Synonyms Z-VAD-AMC
Molecular Formula C₃₀H₃₄N₄O₉
Relative Molecular Mass 594.62
CAS Registry Number [219137-91-4]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords ICE substrate
Areas of Interest Apoptosis & Necrosis
Links / Documents:
Brochures:

Bachem product citations

J.Shi et al., Nature, 514, 187 (2014)
A.Sparsa et al., Oncol. Rep., 29, 1196 (2013)
A.Sparsa et al., Oncol. Rep., 29, 1196 (2013)
J.W.Kim et al., J. Biol. Chem., 275, 8121 (2000)

Product citations

S.A.Loddick et al., NeuroReport, 7, 1465 (1996)

4027536

Enzyme Substrates Inhibitors
Caspase-1 (ICE)