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4027532

Availability: In stock

Z-Tyr-Val-Ala-DL-Asp-fluoromethylketone

4027532

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4027532.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 204.00
CHF 189.72 (7%)
4027532.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 816.00
CHF 758.88 (7%)

Details

Z-YVAD-FMK, a cell-permeable potent irreversible inhibitor of caspase-1 and -4.
Catalog Number N-1595
APC Number 81-4-03
Synonyms Z-YVAD-FMK, Z-Tyr-Val-Ala-DL-Asp-FMK
Molecular Formula C₃₀H₃₇FN₄O₉
Relative Molecular Mass 616.64
CAS Registry Number [1926163-56-5]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Caspase-1 inhibitor
Areas of Interest Apoptosis & Necrosis
Links / Documents:
Brochures:

Bachem product citations

O.Burgy et al., Respir. Res., 17, 162 (2016)
H.Wang et al., Cell Rep., 12, 42 (2015)
Y.Suzuki et al., FEBS J., 277, 4873 (2010)
M.Bachmann et al., Cell. Microbiol., 8, 289 (2006)
S.Kumar et al., Cell Cycle, 4, 1667 (2005)
S.Misaghi et al., Chem. Biol., 11, 1677 (2004)
S.Misaghi et al., Chem. Biol., 11, 1677 (2004)
M.Singh et al., J. Neurochem., 77, 466 (2001)

Product citations

D.M.Zisterer et al., J. Pharmacol. Exp. Ther., 293, 48 (2000)
J.W.Allen et al., FASEB J., 13, 1875 (1999)
S.Zhuang et al., Exp. Cell Res., 250, 203 (1999)
B.A.Eldadah et al., J. Neurosci., 17, 6105 (1997)

4027532

Enzyme Substrates Inhibitors
Caspase-1 (ICE)    
Caspase-4 (TX; ICH-2; ICErel-II)