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4027524

Availability: In stock

Z-Asp-Glu-Val-Asp-chloromethylketone

4027524

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4027524.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 368.00
CHF 342.24 (7%)
4027524.0025 25 mg Ships within 3-5 business days  
CHF 1,471.00
CHF 1,368.03 (7%)

Details

Z-DEVD-CMK reversibly inhibits caspase-3.
Catalog Number N-1580
APC Number 81-6-24
Synonyms Z-DEVD-CMK
Molecular Formula C₂₇H₃₅ClN₄O₁₂
Relative Molecular Mass 643.05
CAS Registry Number [250584-13-5]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Caspase-3 inhibitor
Areas of Interest Apoptosis & Necrosis
Links / Documents:
Brochures:

Bachem product citations

G.M.Ajabnoor et al., Cell Death Dis., 3, e260 (2012)
J.Radhakrishnan et al., Am. J. Physiol. Heart Circ. Physiol., 296, H1164 (2009)
J.Melendez et al., J. Biol. Chem., 279, 53516 (2004)
S.Misaghi et al., Chem. Biol., 11, 1677 (2004)
S.Misaghi et al., Chem. Biol., 11, 1677 (2004)
W.F.Holmes et al., Oncogene, 22, 6377 (2003)
J.Rozman-Pungercar et al., Cell Death Differ., 10, 881 (2003)
M.Kyoung et al., Biochim. Biophys. Acta, 1598, 74 (2002)
M.Vidal-Sanz et al., Neurotox. Res., 2, 215 (2000)
P.Kermer et al., FEBS Lett., 453, 361 (1999)
I.Marzo et al., FEBS Lett., 427, 198 (1998)

Product citations

S.Bourteele et al., J. Biol. Chem., 273, 31245 (1998)
R.Schäfer et al., Exp. Cell Res., 240, 28 (1998)

4027524

Enzyme Substrates Inhibitors
Caspase-3 (CPP-32; Yama; Apopain)    
Caspase-7 (ICE-LAP3; Mch3; CMH-1)