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4027524

Availability: In stock

Z-Asp-Glu-Val-Asp-chloromethylketone

4027524

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4027524.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 368.00
CHF 342.24 (7%)

Details

Z-DEVD-CMK reversibly inhibits caspase-3.
Catalog Number N-1580
APC Number 81-6-24
Synonyms Z-DEVD-CMK
Molecular Formula C₂₇H₃₅ClN₄O₁₂
Relative Molecular Mass 643.05
CAS Registry Number 250584-13-5
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Caspase-3 inhibitor
Application Apoptosis & Necrosis
Links / Documents:

Bachem product citations

G.M.Ajabnoor et al., Cell Death Dis., 3, e260 (2012)
J.Radhakrishnan et al., Am. J. Physiol. Heart Circ. Physiol., 296, H1164 (2009)
J.Melendez et al., J. Biol. Chem., 279, 53516 (2004)
S.Misaghi et al., Chem. Biol., 11, 1677 (2004)
S.Misaghi et al., Chem. Biol., 11, 1677 (2004)
J.Rozman-Pungercar et al., Cell Death Differ., 10, 881 (2003)
W.F.Holmes et al., Oncogene, 22, 6377 (2003)
M.Kyoung et al., Biochim. Biophys. Acta, 1598, 74 (2002)
M.Vidal-Sanz et al., Neurotox. Res., 2, 215 (2000)
P.Kermer et al., FEBS Lett., 453, 361 (1999)
I.Marzo et al., FEBS Lett., 427, 198 (1998)

Product citations

R.Schäfer et al., Exp. Cell Res., 240, 28 (1998)
S.Bourteele et al., J. Biol. Chem., 273, 31245 (1998)

4027524

Enzyme Substrates Inhibitors
"Caspase-3 (CPP-32; Yama; Apopain)    
Caspase-7 (ICE-LAP3; Mch3; CMH-1)"