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Details
Biotinylated derivative of PPACK (N-1065), a potent irreversible inhibitor of thrombin, tissue plasminogen activator (tPA), factor VIIa, and factor Xa. The inhibitor covalently binds to the enzymes and thereby inactivates them. Bound biotin allows reaction with avidin under a variety of different conditions. A procedure has for example been developed to remove active enzyme from zymogen preparations.
Catalog Number
N-1565
APC Number
81-4-58
One Letter Code
Biotinyl-LC-fPR-CMK
Synonyms
Biotinyl-εAhx-D-Phe-Pro-Arg-chloromethylketone
Molecular Formula
C₃₇H₅₆ClN₉O₆S
Relative Molecular Mass
790.43
CAS Registry Number
131104-10-4
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Xa inhibitor; Biotin
Links / Documents:
Bachem product citations
Product citations
4027521
| Enzyme | Substrates | Inhibitors |
|---|---|---|
| Coagulation Factor Xa | ||
| t-Plasminogen Activator | ||
| Thrombin (Coagulation Factor IIa) | ||
| Coagulation Factor VIIa |
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