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4027521

Availability: In stock


Biotinyl-ε-aminocaproyl-D-Phe-Pro-Arg-chloromethylketone

4027521

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4027521.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 462.00
CHF 429.66 (7%)
4027521.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1,849.00
CHF 1,719.57 (7%)

Details

Biotinylated derivative of PPACK (N-1065), a potent irreversible inhibitor of thrombin, tissue plasminogen activator (tPA), factor VIIa, and factor Xa. The inhibitor covalently binds to the enzymes and thereby inactivates them. Bound biotin allows reaction with avidin under a variety of different conditions. A procedure has for example been developed to remove active enzyme from zymogen preparations.
Catalog Number N-1565
APC Number 81-4-58
One Letter Code Biotinyl-LC-fPR-CMK
Synonyms Biotinyl-εAhx-D-Phe-Pro-Arg-chloromethylketone
Molecular Formula C₃₇H₅₆ClN₉O₆S
Relative Molecular Mass 790.43
CAS Registry Number 131104-10-4
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Xa inhibitor; Biotin
Areas of Interest Biotinylated Peptides
Cardiovascular System & Diseases
Hematology
Links / Documents:

Bachem product citations

R.Hartmann et al., J. Thromb. Haemost., 7, 1656 (2009)

Product citations

E.B.Williams et al., J. Biol. Chem., 264, 7536 (1989)

4027521

Enzyme Substrates Inhibitors
Coagulation Factor Xa    
t-Plasminogen Activator    
Thrombin (Coagulation Factor IIa)    
Coagulation Factor VIIa    
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