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Details
This peptide inhibited calmodulin-dependent activation of the smooth muscle myosin light chain kinase with an IC₅₀ of 46 nM. At saturating concentrations of calmodulin, it inhibited myosin light chain and synthetic peptide substrate phosphorylation competitively with IC₅₀ values of 2.7 and 0.9 µM, respectively.
Catalog Number
H-3554
One Letter Code
AKKLSKDRMKKYMARRKWQKTG-NH₂
Molecular Formula
C₁₂₀H₂₀₉N₄₁O₂₈S₂
Relative Molecular Mass
2738.37
CAS Registry Number
313642-00-1
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Links / Documents:
Bachem product citations
Product citations
4026869
Enzyme | Substrates | Inhibitors |
---|---|---|
Myosin-Light-Chain Kinase |