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4026869

Availability: In stock

Myosin Light Chain Kinase (480-501)
H-Ala-Lys-Lys-Leu-Ser-Lys-Asp-Arg-Met-Lys-Lys-Tyr-Met-Ala-Arg-Arg-Lys-Trp-Gln-Lys-Thr-Gly-NH₂

4026869

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4026869.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 210.00
CHF 195.30 (7%)

Details

This peptide inhibited calmodulin-dependent activation of the smooth muscle myosin light chain kinase with an IC₅₀ of 46 nM. At saturating concentrations of calmodulin, it inhibited myosin light chain and synthetic peptide substrate phosphorylation competitively with IC₅₀ values of 2.7 and 0.9 µM, respectively.
Catalog Number H-3554
One Letter Code AKKLSKDRMKKYMARRKWQKTG-NH₂
Molecular Formula C₁₂₀H₂₀₉N₄₁O₂₈S₂
Relative Molecular Mass 2738.37
CAS Registry Number 313642-00-1
Source Synthetic
Storage Conditions -20 ± 5 °C
Links / Documents:

Bachem product citations

R.Kast et al., Br. J. Pharmacol., 152, 1070 (2007)

Product citations

B.E.Kemp et al., J. Biol. Chem., 262, 2542 (1987)

4026869

Enzyme Substrates Inhibitors
Myosin-Light-Chain Kinase