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Details
Ac-YVAD-AOMK is a highly selective, competitive and irreversible inhibitor of caspase-1 (ICE). Ac-YVAD-AOM inactivates the enzyme with a rate limited by diffusion and is relatively inert toward other bionucleophiles such as glutathione, making it an excellent candidate for in vivo studies of enzyme inhibitors.
Catalog Number
N-1520
APC Number
81-7-16
Synonyms
Ac-YVAD-2,6-dimethylbenzoyloxymethylketone, Ac-YVAD-AOM
Molecular Formula
C₃₃H₄₂N₄O₁₀
Relative Molecular Mass
654.72
CAS Registry Number
154674-81-4
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
ICE inhibitor
Areas of Interest
Apoptosis & Necrosis
Links / Documents:
Brochures:
Bachem product citations
Product citations
4026867
| Enzyme | Substrates | Inhibitors |
|---|---|---|
| Caspase-1 (ICE) |
