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Details
The inactive NPY carboxy-terminal pentapeptide (IC₅₀ > 100 µM) was modified by replacing threonine with histidine and glutamine with leucine. The resulting peptide had a dramatically improved affinity (IC₅₀ = 0.45 µM) for the rat brain receptor.
Catalog Number
H-3544
One Letter Code
HRLRY-NH₂
Molecular Formula
C₃₃H₅₄N₁₄O₆
Relative Molecular Mass
742.88
CAS Registry Number
168916-68-5
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Obesity Research
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