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4026747

Availability: In stock

H-Ala-Pro-AFC

4026747

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4026747.0050 50 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 462.00
CHF 429.66 (7%)
4026747.0250 250 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1,849.00
CHF 1,719.57 (7%)
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Details

Fluorogenic substrate for dipeptidyl peptidase IV (DPP IV) and Xaa-Pro dipeptidase. Substrate for fibroblast activation protein alpha (FAP, also called antiplasmin-cleaving enzyme, APCE).
Catalog Number I-1680
One Letter Code AP-AFC
Molecular Formula C₁₈H₁₈F₃N₃O₄
Relative Molecular Mass 397.35
CAS Registry Number [125791-92-6]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Fluorogenic DPP IV substrate; APCE substrate
Areas of Interest Hematology
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Bachem product citations

S.Steven et al., BR. J. Pharmacol., 174, 1620 (2017)
G.Schnapp et al., J. Med. Chem., 59, 7466 (2016)
M.Chen et al., Sci. Rep., 5, 14421 (2015)
F.M.Keane et al., FEBS Open Bio, 4, 43 (2014)
P.Shah et al., J. Clin. Endocrinol. Metab., 98, E1163 (2013)
M.Kern et al, PLoS One, 7, e38744 (2012)
K.M.Chung et al., Protein Sci., 19, 1627 (2010)
C.Ospelt et al., Arthritis Rheum., 62, 1224 (2010)
S.Aggarwal et al., Biochemistry, 47, 1076 (2008)
B.Lee et al., Eur. J. Pharmacol., 589, 306 (2008)
T.Chen et al., Biochim. Biophys. Acta, 1764, 33 (2006)
D.M.Yu et al., FEBS J., 273, 2447 (2006)
K.Ajami et al., Biochim. Biophys. Acta, 1679, 18 (2004)
K.Ajami et al., Biochemistry, 42, 694 (2003)
B.Leiting et al., Biochem. J., 371, 525 (2003)
J.Niedermeyer et al., Eur. J. Biochem., 254, 650 (1998)

Product citations

K.Aertgeerts et al., Protein Sci., 13, 145 (2004)
K.Aertgeerts et al., Protein Sci., 13, 412 (2004)
R.Thomas et al., Structure, 11, 947 (2003)
B.Leiting et al., Biochem. J., 371, 525 (2003)
S.Sun et al., Protein Expr. Purif., 24, 274 (2002)
J.E.Park et al., J. Biol. Chem., 274, 36505 (1999)

4026747

Enzyme Substrates Inhibitors
X-Pro Dipeptidase    
Antiplasmin-cleaving Enzyme (APCE)    
Dipeptidyl-Peptidase IV (DPP IV)    
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