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Astressin trifluoroacetate salt
H-D-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Nle-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-cyclo(-Glu-Ala-His-Lys)-Asn-Arg-Lys-Leu-Nle-Glu-Ile-Ile-NH₂ trifluoroacetate salt


Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4026664.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 263.00
CHF 244.59 (7%)
4026664.1000 1 mg Ships within 3-5 business days  
CHF 442.00
CHF 411.06 (7%)
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The Glu³⁰ to Lys³³ lactam bridge constrains astressin in an α-helical conformation which seems to be responsible for its especially high CRF antagonist activity. Astressin is 100 times more potent than α-helical CRF (9-41) (H-2040) at inhibiting ACTH secretion in vitro, and more than 10 times more potent in vivo than any other CRF antagonist reported to date.
Catalog Number H-3422
APC Number 34-0-14
Synonyms (D-Phe¹²,Nle²¹·³⁸,Glu³⁰,Lys³³)-CRF (12-41) (human, rat), (D-Phe¹²,Nle²¹·³⁸,cyclo(Glu³⁰-Lys³³))-CRF (12-41) (human, rat)
Molecular Formula C₁₆₁H₂₆₉N₄₉O₄₂
Relative Molecular Mass 3563.24
CAS Registry Number [170809-51-5] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Corticorelin (CRF) antagonist