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Details
MUT 1, a tumor-associated antigen peptide originally isolated from the mouse Lewis lung carcinoma, appears to be a fragment of the gap junction protein connexin 37, mutated at position 54. MUT 1 induces effective antitumor cytotoxic T lymphocytes and mediates protection against metastasis, as well as rejection of established metastasis. This is the first description of peptide vaccine efficacity in treatment of residual tumors.
Catalog Number
H-3458
One Letter Code
FEQNTAQP
Synonyms
MUT 1 (human, mouse, rat), (Gln⁵³)-Gap Junction α-4 Protein (51-58) (human, mouse, rat), (Gln⁵³)-Cx37 (51-58) (human, mouse, rat)
Molecular Formula
C₄₀H₅₉N₁₁O₁₅
Relative Molecular Mass
933.97
CAS Registry Number
[155893-22-4]
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Areas of Interest
Cancer Research
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