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4026411

Availability: In stock

(Ile⁷⁶)-TNF-α (70-80) (human)
H-Pro-Ser-Thr-His-Val-Leu-Ile-Thr-His-Thr-Ile-OH

4026411

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4026411.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 232.00
CHF 215.76 (7%)

Details

The peptide PSTHVLITHTI corresponds to residues 70-80 of human TNF-α substituted with Ile at position 76 and exhibits many of the biological activities found for TNF-α. (Ile⁷⁶)-TNF-α (70-80) has been shown to enhance human polymorphonuclear-mediated killing of Plasmodium falciparum in vitro and to reduce Plasmodium chabaudi parasitemia in mice. However, in vivo toxicity studies showed that (Ile⁷⁶)-TNF-α (70-80) does not possess the typical toxic effects of TNF.
Catalog Number H-2698
One Letter Code PSTHVLITHTI
Molecular Formula C₅₅H₉₁N₁₅O₁₆
Relative Molecular Mass 1218.42
CAS Registry Number 163045-82-7
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Apoptosis & Necrosis
Links / Documents:

Product citations

L.M.Kumaratilake et al., J. Clin. Invest., 95, 2315 (1995)