α-Synuclein (61-95) (human) 4026207 | Bachem https://shop.bachem.com/4026207.html

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α-Synuclein (61-95) (human) trifluoroacetate salt
H-Glu-Gln-Val-Thr-Asn-Val-Gly-Gly-Ala-Val-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-Gln-Lys-Thr-Val-Glu-Gly-Ala-Gly-Ser-Ile-Ala-Ala-Ala-Thr-Gly-Phe-Val-OH trifluoroacetate salt

4026207

Product No.	Pack Size	Available	ADS InfoAnalytical Data Sheet	List Price	Online Order Price	Qty
4026207.0500	0.5 mg	Ships within 1 business day	ADSExemplary Data Sheet of a current available lot.	CHF 199.00	CHF 185.07 (7%)
4026207.1000	1 mg	Ships within 3-5 business days		CHF 358.00	CHF 332.94 (7%)

Details

The 35 amino acid peptide NAC (α-synuclein (61-95)) has originally been isolated from the insoluble core of Alzheimer's disease (AD) amyloid plaque. The sequence corresponds to a fragment of a 140 amino acid precursor known as NACP or α-synuclein and was found to form amyloid fibrils via a nucleation-dependent polymerization mechanism. Accumulation of NAC aggregates in the synapse might be responsible for the neurodegeneration in AD and in the prion diseases.

Catalog Number H-2598

APC Number 62-5-25

One Letter Code EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFV

Synonyms NAC, Non-Aβ Component of Alzheimer's Disease Amyloid, Non-β-Amyloid Component of Alzheimer's Disease (NAC)

Molecular Formula C₁₄₁H₂₃₅N₃₉O₄₉

Relative Molecular Mass 3260.65

CAS Registry Number 154040-19-4

Source Synthetic

Storage Conditions -20 ± 5 °C

Application Alzheimer's Disease
Parkinson's Disease

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