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Octadecylphosphophosphoniumcholine is the phosphonium homolog of octadecylphosphocholine.
Octadecylphosphophosphoniumcholine has been shown to be much better tolerated than octadecylphosphocholine in rats suffering from experimental carcinom (LD₅₀= 1.8 mmol/kg in mouse) The cytotoxic activity on carcinoma cell cultures remained as good as that of octadecylphosphocholine, with an EC₉₀ of 6.2 µmol/L as compared to 6.4 µmol/L for octadecylphosphocholine.
Octadecylphosphophosphoniumcholine has been shown to be much better tolerated than octadecylphosphocholine in rats suffering from experimental carcinom (LD₅₀= 1.8 mmol/kg in mouse) The cytotoxic activity on carcinoma cell cultures remained as good as that of octadecylphosphocholine, with an EC₉₀ of 6.2 µmol/L as compared to 6.4 µmol/L for octadecylphosphocholine.
Catalog Number
O-1550
Molecular Formula
C₂₃H₅₀O₄P₂
Relative Molecular Mass
452.60
CAS Registry Number
[156825-89-7]
Storage Conditions
-20 ± 5 °C
Keywords
Anti-cancer phospholipid
Areas of Interest
Cancer Research
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Product citations
J.Stekar et al.,
Angew. Chem. Int. Ed. Engl.,
34,
238 (1995)
