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Details
Intermediate for the synthesis of IL-1β converting enzyme (ICE, caspase-1) inhibitors or other inhibitors containing a C-terminal aspartyl residue modified by different methylketone derivatives. According to Németh el al., who detected an antiapoptotic activity for the compound itself, it may be used for studying the early events of apoptosis in some cell types.
Catalog Number
N-1425
Molecular Formula
C₁₇H₂₂BrNO₅
Relative Molecular Mass
400.27
CAS Registry Number
153088-76-7
Storage Conditions
-20 ± 5 °C
Keywords
ICE inhibitor
Application
Apoptosis & Necrosis
Links / Documents:
Product citations
K.Németh et al.,
Int. J. Immunopharmacol.,
19,
215 (1997)