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Details
This derivative suitable for iodination is a further development of natural MCH, which loses its activity upon iodination. The labeled compound enabled to establish the first radioreceptor assay for MCH. Saturation binding experiments with this peptide, radioiodinated, revealed a Bmax of 1090 and a Kd of 1 · 10⁻¹⁰M for receptors in G4F-7 mouse melanoma cells.
Catalog Number
H-2218
One Letter Code
DFDMLRCMLGRVFRPCWQY
Synonyms
(Phe¹³,Tyr¹⁹)-Melanin-Concentrating Hormone (MCH) (human, mouse, rat)
Molecular Formula
C₁₀₉H₁₆₀N₃₀O₂₆S₄
Relative Molecular Mass
2434.92
CAS Registry Number
160201-86-5
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Pituitary & Hypothalamic Hormones
Links / Documents:
Bachem product citations
Product citations
R.Drozdz et al.,
Peptides 1994, Proceedings of the 23rd European Peptide Symposium, Braga, p. 785, H.L.S.Maia, ed., Escom, Leiden,
(1995)