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Availability: In stock

Z-Phe-Lys-2,4,6-trimethylbenzoyloxy-methylketone trifluoroacetate salt


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4025803.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 757.00
CHF 704.01 (7%)


Z-FK-ck is a very effective in vivo cathepsin B inhibitor in rats. It inhibited rat liver cathepsin B activity ex vivo with ED₅₀ = 5 mg/kg intraperitoneally and 18 mg/kg orally at 4-5 h postdose, and 2.4 mg/kg subcutaneously at 24 h postdose. It also inhibited rat cathepsin B activity in heart and skeletal muscle with ED₅₀ = 0.1 and 1.0 mg/kg subcutaneously at 20 h postdose. Z-FK-ck is an inhibitor of gingipain K.
Catalog Number N-1400
Synonyms Z-FK-ck
Molecular Formula C₃₄H₄₁N₃O₆
Relative Molecular Mass 587.72
CAS Registry Number 118253-05-7
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Cathepsin B inhibitor


Enzyme Substrates Inhibitors
Cathepsin B    
Gingipain K