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4025760

Availability: In stock

Acetyl-Amyloid β/A4 Protein Precursor₇₇₀ (96-110) (cyclized)
Ac-Asn-Trp-Cys-Lys-Arg-Gly-Arg-Lys-Gln-Cys-Lys-Thr-His-Pro-His-NH₂ (Disulfide bond)

4025760

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4025760.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 105.00
CHF 97.65 (7%)

Details

This cyclized peptide which is homologous to the heparin-binding domain of APP, binds strongly to heparin and inhibits binding of ¹²⁵I-labeled APP to heparin (IC₅₀= 10⁻⁷M). The peptide blocks the heparan sulfate proteoglycan-dependent stimulatory effect of APP on neurite outgrowth.
Catalog Number H-2232
APC Number 62-1-15
One Letter Code Ac-NWCKRGRKQCKTHPH-NH₂
Synonyms β-Amyloid / A4 Protein Precursor (APP) (96-110), analog, Ac-APP₇₇₀ (96-110) (cyclized)
Molecular Formula C₈₁H₁₂₈N₃₂O₁₉S₂
Relative Molecular Mass 1918.24
CAS Registry Number 289634-54-4
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Alzheimer's Disease
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Product citations

D.H.Small et al., J. Neurosci., 14, 2117 (1994)