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Details
The remarkable histochemical features of Alzheimer's disease (AD) are plaques that contain cores of extracellular filaments, which have been identified as amyloid substance. The major component of this amyloid is the β-protein. The synthetic peptide, having the same sequence as the N-terminal 28 residues, formed fibrils that have the same antigenic and structural features like the native AD amyloid filaments.
Catalog Number
H-7865
APC Number
62-0-74
One Letter Code
DAEFRHDSGYEVHHQKLVFFAEDVGSNK
Synonyms
Alzheimer's Disease β-Protein (SP28), β-Amyloid (1-28)
Molecular Formula
C₁₄₅H₂₀₉N₄₁O₄₆
Relative Molecular Mass
3262.50
CAS Registry Number
109770-29-8
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Amyloidogenic peptide
Application
Alzheimer's Disease
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