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Ac-Trp-3,5-bis(trifluoromethyl)benzyl ester


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price
4025344.0250 250 mg Request lead time  
CHF 315.00
CHF 292.95 (7%)


In vitro, L-732'138 displaced [¹²⁵I]substance P (SP) from the cloned NK-1 receptor expressed in Chinese hamster ovary cells with IC₅₀ = 1.6 nM. It inhibited competitively SP-induced inositol phosphate accumulation in these cells with Kb = 25 nM. Affinity for NK-2 and NK-3 receptors was weaker than 5 μM.
Catalog Number E-3135
Synonyms L-732138
Molecular Formula C₂₂H₁₈F₆N₂O₃
Relative Molecular Mass 472.39
CAS Registry Number 148451-96-1
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords NK1 antagonist
Application Cancer Research