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Details
It has been demonstrated that the RGD-containing peptide, c(GRGDSPA), inhibited the binding of fibronectin to stimulated platelets with IC₅₀= 0.223 µM. c(GRGDSPA) also blocked thrombin-induced platelet aggregation with IC₅₀= 32 µM, but was less potent than native fibronectin in this respect.
Catalog Number
H-1986
Synonyms
cyclic GRGDSPA
Molecular Formula
C₂₅H₄₀N₁₀O₁₀
Relative Molecular Mass
640.65
CAS Registry Number
[128857-77-2]
Source
Synthetic
Storage Conditions
-20 ± 5 °C
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Bachem product citations
4025337
| Enzyme | Substrates | Inhibitors |
|---|---|---|
| Thrombin (Coagulation Factor IIa) |
