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Details
The azido group is sensitive towards piperidine. In Fmoc-SPPS, this derivative is best introduced as N-terminus or modified before elongating the peptide.
Fmoc-p-azidophenylalanine may be inserted as a precursor of p-aminophenylalanine. Levinson et al. reduced the azido group on-resin with a large excess of tributylphosphine in DMF.
Catalog Number
B-2360
Molecular Formula
C₂₄H₂₀N₄O₄
Relative Molecular Mass
428.45
CAS Registry Number
163217-43-4
Storage Conditions
-20 ± 5 °C
Links / Documents:
Brochures:
Bachem product citations
Product citations
T.J.Elliot et al.,
Protein Pept. Lett.,
1,
193 (1994)
A.N.Eberle et al.,
Innov. Persp. Solid Phase Synthesis (R.Epton, ed.), Intercept, Andover (UK),
95 (1992)
