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Details
Using the anticomplementarity hypothesis, a peptide mimic of the vitronectin binding site on the platelet fibrinogen receptor was designed. The resulting pentapeptide EHIPA binds fibrinogen and inhibits both platelet aggregation and the adhesion of platelets to fibrinogen and vitronectin. EHIPA therefore has the potential of being used as an antithrombotic agent.
Catalog Number
H-8635
One Letter Code
EHIPA
Molecular Formula
C₂₅H₃₉N₇O₈
Relative Molecular Mass
565.63
CAS Registry Number
137235-80-4
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Inhibitor of platelet aggregation and adhesion of fibrin
Application
Cardiovascular System & Diseases
Hematology
Hematology
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