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4018735

Availability: In stock

Boc-Arg-Val-Arg-Arg-AMC acetate salt

4018735

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4018735.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 263.00
CHF 244.59 (7%)
4018735.0100 100 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 788.00
CHF 732.84 (7%)
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Details

The fluorogenic substrate Boc-RVRR-AMC is efficiently cleaved by furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km approx. 4·10³ M⁻¹s⁻¹). As a calcium-dependent serine protease associated with Golgi membranes, furin is responsible for the secretory processing of precursor proteins at paired basic residues. Boc-RVRR-AMC is also cleaved by proprotein convertase 4.
Stock solutions of Boc-RVRR-AMC are best prepared in DMSO.
Catalog Number I-1645
APC Number 81-7-40
One Letter Code Boc-RVRR-AMC
Molecular Formula C₃₈H₆₂N₁₄O₈
Relative Molecular Mass 843.01
CAS Registry Number [136132-77-9] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Furin substrate
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Bachem product citations

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Product citations

A.Basak et al., Protein Expr. Purif., 60, 117 (2008)
K.Hatsuzawa et al., J. Biol. Chem., 267, 16094 (1992)
S.S.Molloy et al., J. Biol. Chem., 267, 16396 (1992)

4018735

Enzyme Substrates Inhibitors
Furin    
Proprotein Convertase 4